Clinical Support

SierraSil® has been subjected to a rigorous level of testing and analysis. From these extensive assessments, experts agree that SierraSil® is safe and effective and promotes joint health and function.*

1. HUMAN CLINICAL STUDY

A multi-center, double-blind, randomized, placebo-controlled study of more than 100 patients needing joint support was conducted at four different servings (three with SierraSil®, one with placebo). This study was published in a peer-reviewed journal.

Internationally Registered, Multi-Center, Randomized, Double-Blind, Placebo-Controlled Trial #ISRCTN38432711. PUBLISHED: The Journal of Inflammation.

RESULTS: This study provides clear evidence that SierraSil®, at 3 and 2 capsules, may provide some joint support within two weeks of daily use*.

2. MECHANISM OF ACTION STUDY

This test was undertaken to determine how SierraSil® worked on human cartilage in-vitro. The test demonstrated that SierraSil® promoted cartilage health, measured by the reduced amount of degraded cartilage debris, as glycosaminoglycans (GAG) release.*

Miller, Mark J.S., Ahmed, S. et al. 2004. Suppression of Human Cartilage Degradation and Chondrocyte Activation by a Unique Mineral Supplement (SierraSil®) and a Cat’s Claw Extract, Vincaria®. Journal of the American Nutraceutical Association. Vol. 7. No. 2:32-39.

3. HUMAN PILOT STUDY

SierraSil® was tested to determine if it safely provided significant support to knees*.

WOMAC (Western Ontario and McMaster Osteoarthritis Index) scoring.

4. DISSOLUTION TEST (BIOACCESSIBILITY)

A sample of SierraSil® was tested to determine the bioaccessibility of minerals.

RESULTS: The bioaccessibility of aluminum, lead and iron was found to be very low.

Protocol: US Pharmacopeia 24 Method 711

5. SUB-ACUTE ORAL TOXICITY STUDY

A daily serving of SierraSil® up to 1,000 mg/kg (35 times the recommended serving) for a period of 90 days was tested.

RESULTS: SierraSil® did not cause any adverse responses at the highest level taken.

Protocol: OECD No. 408

Research

The consistent outcome of the lab, invitro and human clinical trials are that SierraSil is a safe and effective way to support joint health and function*. Research also shows that the benefits of SierraSil are usually felt within 14 days or less.

SierraSil is therefore an exceptional natural product for people who need joint and cartilage support.* Among natural products SierraSil is one of the most consistent alternative. Please explore this section for a closer look at the research.